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    hub sciencedirect scopus applications register login login go to scival suite username: password: remember me | not registered? viagra online cheap Forgotten your username or password? no prescription buy viagra Go to athens / institution login remote access activation home publications search my settings my alerts shopping cart help export citation purchase more options... Email article signed up for journal alerts [remove] alert me about new articles in this journal your selection(s) could not be saved due to an internal error. Please try again. Search     all fields     author advanced search     journal/book title     volume   issue   page search tips article outline is loading... Javascript required for article outline gastroenterology volume 120, issue 4, march 2001, pages 841–847 backwash ileitis is strongly associated with colorectal carcinoma in ulcerative colitis udo a. Heuschen * , , 2 , , ulf hinz † , erik h. Allemeyer * , josef stern ‖ , matthias lucas * , frank autschbach § , christian herfarth * , gundi heuschen * * department of surgery, university of heidelberg, germany † unit for documentation and statistics of the department of surgery, university of heidelberg, germany § department of pathology, university of heidelberg, germany ‖ st. Josefs-hospital, dortmund, germany received 15 august 2000 accepted 26 october 2000 available online 16 may 2002 how to cite or link using doi permissions & reprints view full text purchase $31. 50 materials and methods results discussion references abstract background & aims: commonly accepted risk factors for colorectal carcinoma (crc) in ulcerative colitis are duration and extent of disease. By identifying still unknown risk factors, surveillance strategies may be improved further. We investigated whether backwash ileitis is also a factor associated with crc in ulcerative colitis. Methods: five hundred ninety consecutive patients with ulcerative colitis who received restorative proctocolectomy were classified into 3 groups: (1) pancolitis with backwash ileitis, (2) pancolitis without backwash ileitis, and (3) left-sided colitis. The association with crc was analyzed in these 3 groups of patients. buy pill viagra As further risk factors, we investigated disease duration, dysplasia, primary sclerosing cholangitis, age at diagnosis of disease, disease activity, and gender. Univariate and multivariate logistic regression were used for analysis. Results: crc was diagnosed in 11. 2% of all patients. Crc was found in 29. 0% of 107 patients in group 1, compared with 9. 0% of 369 patients in group 2, and in 1. viagra for sale no prescription 8% of 114 patients in group 3 (p < 0. 001). Cancer patients in group 1 showed significantly more multiple tumor growth (45. 2%) than patients in group 2 (24. 2%) and group 3 (0%) (p = 0. 041). Estimating the relative risk for crc in the multivariate analysis, patients in group 1 showed a significantly higher odds ratio than patients in groups 2 and 3 (odds ratio: 19. no prescription buy viagra 36 vs. 9. 58 vs. 1; p < 0. 001). High-grade dysplasia, low-grade dysplasia, disease duration of more than 10 years, and disease duration of less than 10 years in patients older than 45 years were further factors with significantly increased risk (odds ratios: 21. 69, 6. cheap no prescription viagra 36, 3. 63, 4. 37), but primary sclerosing cholangitis was not (p = 0. 080). However, primary sclerosing cholangitis was strongly associated with backwash ileitis. Conclusions: there is a strong association of backwash ileitis with crc in patients with ulcerative colitis who undergo proctocolectomy. The predictive value of backwash ileitis for crc and premalignant dysplasia in patients with ulcerative colitis should be investigated in future studies based on colonoscopic surveillance. Gastroenterology 2001;120:841-847 abbreviations bwi, backwash ileitis; crc, colorectal carcinoma; hgd, high-grade dysplasia; lgd, low-grade dysplasia; psc, primary sclerosing cholangitis figures and tables from this article: table 1. cheap generic india viagra Frequency of crc in specimens of 590 uc patients who underwent restorative proctocolectomy note. The frequency of potentially associated factors in the 3 groups of patients: (1) pancolitis with bwi (n = 107, 18. 2%), (2) pancolitis without bwi (n = 369, 62. 5%), and (3) left-sided colitis (n = 114, 19. 3%). no prescription buy viagra Total numbers of patients are given, with their relative proportion in parentheses (%). Age and disease duration are described as median and interquartile range (iqr). Table options view in workspace table 2. Patients with crc note. Crc, n = 66. Total number of patients is given, with their relative proportion in parentheses (%). price generic viagra Number of carcinomas, localization, and presence of psc are shown in relation to the 3 groups of patients. Malignancies proximal to the splenic flexure were considered as being located in the right, distal to the splenic flexure in the left hemicolon. Table options view in workspace table 3. Univariate analysis of potential risk factors for crc in uc note. N = 590. Total numbers of patients are given, with their relative proportion in parentheses (%). Ci, confidence interval. buy generic viagra online Table options view in workspace table 4. The final model of multiple logistic regression analysis of risk factors independently associated with crc note. N = 584; missing values, n = 6. Table options view in workspace address reprint requests to u. A. Heuschen, m. D. viagra sales , department of surgery, university of heidelberg, kirschnerstr. 1,69120 heidelberg, germany. order viagra without prescription 2 fax: (49) 6221-56-5915. Copyright © 2001 amer.


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